Asawer Abdul-Jabbar Al-Salman

Department of Pathological Analysis, College of Science, Wasit University, Iraq

Abstract

Injectable fillers in the current times are now a pillar in facial rejuvenation and play a key role in ensuring
the success of the treatment. Although their advantages are undeniable, the list of potential complications
(adverse effects that are instant, late, delayed, transient or irreversible) is too long and must be taken into
consideration. The distinction is made between the different filler material, these effects are attributed to
findings of the histopathology and to the existing treatment options.
Background
Injectable hyaluronic acid is one of the temporary dermal fillers. The concentration of hyaluronic acid can
be found naturally in all parts of the body with the highest concentration found in the joints, eyes and the
skin. Hyaluronic acid injected is intended to minimize the effect of fine lines, wrinkles, folds of the face,
structure, framework, and volume of the face and lips.
Aims: In order to assess the degradation and alterations within the tissue after hyaluronic acid (HA) filler
injections with special attention paid to crosslinking agents, degradation and tissue reactions..

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